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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LENG8 All Species: 14.55
Human Site: Y674 Identified Species: 29.09
UniProt: Q96PV6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PV6 NP_443157.1 779 86129 Y674 T A W A L G N Y H R F F R L Y
Chimpanzee Pan troglodytes XP_001174961 779 86160 Y674 T A W A L G N Y H R F F R L Y
Rhesus Macaque Macaca mulatta XP_001084592 751 82765 R654 V A H A L A L R T A W A L G N
Dog Lupus familis XP_533588 866 95014 Y706 A A W A L G N Y H R F F R L Y
Cat Felis silvestris
Mouse Mus musculus Q8CBY3 785 86748 Y671 T A Y R I L Y Y I F T K N S G
Rat Rattus norvegicus NP_001032879 846 93215 Y712 A A W A L G N Y H R F F K L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521626 835 91481 F729 A A W A L G N F H R F F R L Y
Chicken Gallus gallus
Frog Xenopus laevis Q32NW2 800 90307 R703 V A H A L S L R E A W A L S N
Zebra Danio Brachydanio rerio A4QNR8 839 92784 R742 V A H A L E L R T A W A L G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609459 874 99101 G731 M L Y M E I G G K N A N A L E
Honey Bee Apis mellifera XP_001121422 801 90250 K676 I L Y Y I F T K N T Q D L T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190105 1466 163799 A1368 H A L E L R S A W A M S D Y H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 85.4 80.1 N.A. 86.3 81.3 N.A. 71.2 N.A. 59.2 48.7 N.A. 28.7 33.5 N.A. 24.4
Protein Similarity: 100 99.4 87.2 83.7 N.A. 89.5 84.5 N.A. 77.7 N.A. 70.3 58.8 N.A. 44.1 46.8 N.A. 33
P-Site Identity: 100 100 20 93.3 N.A. 20 86.6 N.A. 86.6 N.A. 20 20 N.A. 6.6 0 N.A. 13.3
P-Site Similarity: 100 100 26.6 93.3 N.A. 33.3 93.3 N.A. 93.3 N.A. 26.6 26.6 N.A. 13.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 84 0 67 0 9 0 9 0 34 9 25 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % D
% Glu: 0 0 0 9 9 9 0 0 9 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 9 0 9 0 9 42 42 0 0 0 % F
% Gly: 0 0 0 0 0 42 9 9 0 0 0 0 0 17 9 % G
% His: 9 0 25 0 0 0 0 0 42 0 0 0 0 0 9 % H
% Ile: 9 0 0 0 17 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 9 0 0 9 9 0 0 % K
% Leu: 0 17 9 0 75 9 25 0 0 0 0 0 34 50 0 % L
% Met: 9 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 42 0 9 9 0 9 9 0 25 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 9 0 9 0 25 0 42 0 0 34 0 0 % R
% Ser: 0 0 0 0 0 9 9 0 0 0 0 9 0 17 0 % S
% Thr: 25 0 0 0 0 0 9 0 17 9 9 0 0 9 9 % T
% Val: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 42 0 0 0 0 0 9 0 25 0 0 0 0 % W
% Tyr: 0 0 25 9 0 0 9 42 0 0 0 0 0 9 42 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _